SKIN-CAD – Biocom Systems, Inc.

Simulator for Skin Pharmacokinetics

SKIN-CAD® Version 6.1

For more information, please visit this page.

  SKIN-CAD brochure English version (SKIN-CAD610E2.pdf)

Mathematical Models of Transdermal and Topical Drug Delivery, Second Edition
Kakuji Tojo, Ph.D. (Professor, Kyushu Institute of Technology, Fukuoka, Japan)
ISBN 4-9901108-2-X (978-4-9901108-2-6)
Print published on September, 2005 / B5-sized 154 pages / Price: JPY5,000

Errata of “Mathematical Models of Transdermal and Topical Drug Delivery, Second Edition” updated on July, 2009  (Errata_TTS2.pdf)

[Contents]
1. Introduction
2. Drug Release from Transdermal Delivery System (revised)
3. Drug Transport Across the Stratum Corneum
4. Nonsteady State Diffusion Model (revised)
5. Effect of Microcirculation (revised)
6. Effect of Skin Binding
7. Drug Metabolism in the Skin (revised)
8. Prediction of Blood Concentration
9. In Vitro Evaluation Method for Model Parameters
10. Prediction of In Vivo Performance
11. Prediction of Penetration Rate Under Iontophoretic Delivery
12. Effect of Ultrasound
13. Effect of Temperature
14. Microneedle Array for Transdermal Drug Delivery
15. Conclusions
16. Appendix 1: Method of Solution
17. Appendix 2: Parameter Values
18. Appendix 3: Dissolution-Matrix Device
19. Appendix 4: Effect of Individual Difference in Pharmacokinetics
20. Appendix 5: Iontophoretic Delivery of Fentanyl, E-TRANS®
21. Appendix 6: Time Lag Controlled Transdermal Delivery System
22. Appendix 7: Transdermal Prodrug Delivery
23. Appendix 8: PC Software for Skin Pharmacokinetics, SKIN-CAD™
References and Notes
Index

 out-of-print

Mathematical Models of Transdermal and Topical Drug Delivery
Kakuji Tojo, Ph.D. (Professor, Kyushu Institute of Technology, Fukuoka, Japan)
ISBN: 4-9901108-1-1 (978-4-9901108-1-9)
Print published on January, 2003 / B5-sized 168 pages / Price: JPY5,000

Errata of “Mathematical Models of Transdermal and Topical Drug Delivery” updated on September, 2007 (Errata_TTS.pdf)